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Postoperative efficacy of PRK correcting mild-to-moderate myopia with low dose mitomycin C administered intraoperatively
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- Author:
- No author available
- Journal Title:
- INTERNATIONAL EYE SCIENCE
- Issue:
- 10
- DOI:
- 10.3969/j.issn.1672-5123.2012.10.47
- Key Word:
- 低浓度;丝裂霉素;屈光性角膜切削术;近视
Abstract： 目的:评价PRK术中应用低浓度(0.02g/L)丝裂霉素(PRK+LMMC)30s治疗低、中度近视眼术后疗效.方法:选取我院接受屈光性角膜切削术(PRK)治疗的30例57眼低、中度近视患者,术中应用0.02g/L的MMC 30s,将术后6mo的随访结果与同期接受准分子激光原位角膜磨镶术(LASIK)治疗的疗效进行比较.结果:术后6mo,PRK+LMMC治疗组等值球镜屈光度0.210D、等值球镜屈光度在±0.50D范围内的发生率71.9%、裸眼视力≥1.0者77.2%,平均最佳矫正视力1.19±0.18;LASIK治疗组等值球镜屈光度-0.017D,等值球镜屈光度在±0.50D范围内的发生率70.1%,裸眼视力≥1.0者72.7%,平均最佳矫正视力1.16±0.19,两组比较差异均无统计学意义(P＞0.05).术后6mo,PRK+LMMC治疗组没有出现超过1级的haze,所有眼最佳矫正视力均好于术前.LASIK治疗组1眼因角膜上皮植入使最佳矫正视力较术前下降3行,其余眼最佳矫正视力均好于术前.结论:PRK术中应用0.02g/L的MMC 30s治疗低、中度近视同LASIK具有同样的视力结果,避免了LASIK瓣的并发症,不失为一个可取的手术程序.
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