Transcatheter aortic valve replacement in elderly patients

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Author:
Dimytri Siqueira(Institute Dante Pazzanese of Cardiology, Av. Dr Dante Pazzanese, 500 Ibirapuera, S(a)o Paulo, CEP 04012080, Brazil)
Alexandre Abizaid(Institute Dante Pazzanese of Cardiology, Av. Dr Dante Pazzanese, 500 Ibirapuera, S(a)o Paulo, CEP 04012080, Brazil)
Magaly Arrais J.(Institute Dante Pazzanese of Cardiology, Av. Dr Dante Pazzanese, 500 Ibirapuera, S(a)o Paulo, CEP 04012080, Brazil)
Eduardo Sousa(Institute Dante Pazzanese of Cardiology, Av. Dr Dante Pazzanese, 500 Ibirapuera, S(a)o Paulo, CEP 04012080, Brazil;Heart Hospital, Rua Desembargador Eliseu Guilherme, 147 Paraíso S(a)o Paulo, CEP 040004030, Brazil)
Journal Title:
JOURNAL OF GERIATRIC CARDIOLOGY
Issue:
Volume 09, Issue 02, 2012
DOI:
10.3724/SP.J.1263.2011.12291
Key Word:
Aortic stenosis;Elderly patients;Transcatheter aortic valve replacement;Percutaneous valve therapies

Abstract: Aortic stenosis is the most common native valve disease, affecting up to 5% of the elderly population. Surgical aortic valve replacement reduces symptoms and improves survival, and is the definitive therapy in patients with symptomatic severe aortic stenosis. However, despite the good results of classic surgery, risk is markedly increased in elderly patients with co-morbidities. Transcatheter aortic valve replacement (TAVR) allows implantation of a prosthetic heart valve within the diseased native aortic valve without the need for open heart surgery and cardiopulmonary bypass, offering a new therapeutic option to elderly patients considered at high surgical risk or with contraindications to surgery. To date, several multicenter registries and a randomized trial have confirmed the safety and efficacy of TAVR in those patients. In this chapter, we review the background and clinical applications of TAVR in elderly patients.

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