Clinical application of portable orgnaophosphorus pesticide East detector

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Journal Title:
Volume 19, Issue 04, 2010
Key Word:
Acute organophosphorus pesticide poisoning(AOPP);Portable orgnaophosphorus pesticide fast detector;Cholinesterase

Abstract: Objective To investigate the clinical application of portable orgnaophosphorus pesticide fast de-tector (abbreviated as Detector). Method The Detector was used in 90 acute pesticide (including orgnaophos-phorus pesticide and non-orgnaophosphorus pesticide) poisoning patients, who were treated in the Emergency De-partment of the First Hospital of Xi' an Jiaotong University from March 2006 to February 2007. The monitored group consisted of 66 patients, who were diagnosed with acute organophosphorus pesticide poisoning (AOPP). The control group consisted of 60 patients, who were diagnosed with AOPP from March 2005 to February 2006. We i-dentified the rapid diagnosis circumstance of the Detector, and compared the cholinesterase activity recovery at 48 h,72 h,96 h, 120 h, 144 hours and discharge between the monitored group and control group by t-test. Results The Detector identified the nature of the toxin quickly (whether poisoned for organophosphate or not). There was no statistically difference in recovery time of ChE activity in the serum of patients with AOPP (mild poisoning)be-tween the control group and the monitored group (P> 0.05). While ChE activity in serum of patients with moder-ate and severe was significantly increased at 48 h,72 h,96 h, 120 h, 144 h and discharge when compared to the control group (P < 0.05). Conclusions The Detector can help doctors quickly identify the nature of the toxin.The result is used to judge whether a gastric lavage is effective.

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