The feature and treatment of kidney stones and acute renal failure in children associated with infant formula adulterated with melamine

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Author:
ZHANG Gui-ju(Department of Nephrology,Beijing children's Hospital affiliated to Capital University of Medical Scicence,Beijing 100045,China)
FAN Jian-feng(Department of Nephrology,Beijing children's Hospital affiliated to Capital University of Medical Scicence,Beijing 100045,China)
CHEN Zhi(Department of Nephrology,Beijing children's Hospital affiliated to Capital University of Medical Scicence,Beijing 100045,China)
JIA Li-qun(Department of Nephrology,Beijing children's Hospital affiliated to Capital University of Medical Scicence,Beijing 100045,China)
SHEN Ying(Department of Nephrology,Beijing children's Hospital affiliated to Capital University of Medical Scicence,Beijing 100045,China)
Journal Title:
CHINESE JOURNAL OF EMERGENCY MEDICINE
Issue:
Volume 17, Issue 12, 2008
DOI:
Key Word:
Children;Melamine;Urinary stone;Acute renal failure

Abstract: Objective To explore the feature and the optimal treatment of kidney stones in children associ-ated with infant formula which had been aduherated with melamine.Method Total of 47 cases of urinary stone and 31 cases of acute renal failure caused by urinary multiple obstruction in children associated with infant formula which had been adulterated with mlelamine in Beijing Children's Hospital University of Medical Science,form Jan-uary to November,2008 were retrospectively analyzed.Results Infant formula which had been adultemted with melamine may lead to kindey stones in 15 days.The mean age was 11-month and the ratio of male to female was 2.6:1.The kindey stones were usually multiple and mostly located either in the ureteropelvic junction or all through the ureter.In the view of the renal function resuming duration,there was no statistic difference among the acute renal failure group,operation group and the conservative group(P=0.683~0.846).In children with uri-nary obstruction and acute renal failure,hemedialysis or peritoneal dialysis was performed.83.9%were relieved by posting catheter through panedoseope and blood purification.100% of the patients resumed normal renal func-tion.81.3% of the patients without acute renal failure had recovered after conservative therapies such as infusion.Conclusions The patients associated with infant formula which had been adulterated with melamine were Usually little infants.Male were more vulnerable than female.Most of them had recovered smoothly and the renal function resumed normal after effcient therapies.

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