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Effects of four different solutions on the early systemic hemodynamics and oxygenation of hemorrhagic shock dogs
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF EMERGENCY MEDICINE
- Issue:
- 1
- DOI:
- 10.3760/j.issn:1671-0282.2007.01.006
- Key Word:
- 小容量复苏;失血性休克;血流动力学
Abstract： 目的 探讨四种不同溶液(高渗盐水、高渗盐水羟乙基淀粉溶液、生理盐水及羟乙基淀粉)对失血性休克犬复苏早期血流动力学、氧代谢动力学的影响.方法 杂种犬32只制备成失血性休克模型,并随机分为4组.分别以6 ml/kg高渗盐水溶液(HS)与6 ml/kg高渗盐水羟乙基淀粉溶液(HSS)对两组失血性休克模型进行容量复苏,而以3倍失血量生理盐水(NS)及等失血容量羟乙基淀粉(HES)对其他两组复苏作对照,观察复苏早期血流动力学、氧代谢动力学指标的变化.结果 四种溶液均能改善失血性休克犬复苏的早期血流动力学、氧代谢动力学及组织灌流,但在30 min后HS、HSS及NS容量指标下降,血流动力学及氧代谢动力学下降,其中HS及NS下降最为明显,其次HSS,而HES能保持相对稳定.结论 小容量高渗盐水在失血性休克模型中复苏有效,其作用与生理盐水类似;小容量高渗盐水加胶体溶液较优于单纯高渗盐水;羟乙基淀粉溶液复苏效果最好且持续长久.
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