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Comparison of primary or facilitated percutaneous coronary interventions for acute myocardial infarction

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Author:: No author available

Journal Title:: CHINESE JOURNAL OF EMERGENCY MEDICINE

Issue:: 10

DOI:: 10.3760/j.issn:1671-0282.2006.10.005

Key Word:: 急性心肌梗死;直接经皮冠状动脉介入术;易化经皮冠状动脉介入术

Abstract：目的比较直接介入与易化介入治疗急性心肌梗死的疗效.方法连续入选急性心肌梗死患者132名,随机分为两组.易化介入组静脉注射普通肝素和重组组织型纤溶酶原激活剂;直接介入组静脉注射安慰剂.然后尽快行经皮冠脉介入治疗.观察30 d全因死亡率、梗死相关血管再闭塞、术前与术后梗死血管开通率、左室射血分数和出血并发症.结果易化介入组与直接介入组30 d死亡率、梗死相关血管再闭塞、左室射血分数、出血并发症差异无显著性(P＞0.05).术前梗死血管开通率易化介入组高于直接介入组[39(59.1%)vs 16(24.2%),P＜0.05];术后血管开通率两组相近[63(95.5%)vs.62(93.9%),P＞0.05].结论急性心肌梗死发病6 h内采用易化介入与直接介入相比,30 d死亡率、左心功能有改善趋势,而出血并发症未见增加,其预后可能优于直接介入治疗.

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