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Timing and effects of fluid resuscitation on vascular visceral permeability in severely burned rats
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF EMERGENCY MEDICINE
- Issue:
- 10
- DOI:
- No doi available
- Key Word:
- 复苏;烧伤;血管通透性
Abstract： 目的探讨不同复苏时机对烧伤延迟复苏大鼠内脏血管通透性的影响.方法64只SD大鼠30%Ⅲ度烫伤后,随机分为烫伤组、早期复苏组、延迟复苏组.伤后9 h取肺、心、肝、肾,测定脏器血管通透性、组织含水量、髓过氧化物酶(MPO)活性.结果与烫伤组和早期复苏组相比,伤后9h延迟复苏组大鼠肺、心、肝、肾的血管通透性、含水量和MPO活性明显增高.结论烧伤延迟复苏大鼠内脏的血管通透性明显增加,中性粒细胞聚集是其重要机制之一.
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