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Significance of monitoring urine and plasma osmotic pressure and sodium concentration in diabetes insipidus and cerebral salt wasting syndrome after traumatic brain injury
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF EMERGENCY MEDICINE
- Issue:
- 2
- DOI:
- 10.3760/j.issn:1671-0282.2005.02.004
- Key Word:
- 尿崩综合征;脑盐耗综合征;渗透压;钠浓度
Abstract： 目的通过前瞻性的临床研究,探讨尿-血渗透压比值和尿-血钠浓度比值监测对脑外伤后尿崩综合征(DI)和脑盐耗综合征(CSW)的意义.方法对并发DI(30例)和CSW(10例)的中重度颅脑损伤患者进行入院后30 d内的尿-血渗透压比值,尿-血钠浓度比值,尿相对密度,24小时尿量和血浆抗利尿激素水平的监测.进行Pearson相关分析.结果 30 d内死亡4例.DI组需要长期激素替代治疗的有11例,其中9例尿-血渗透压比值的最小值为0.219～0.425;治愈19例,其中16例的尿血渗透压比值的最小值是0.437～0.765.DI组确诊后一周内平均尿血渗透压值与血浆抗利尿激素水平有密切相关性(相关系数r=0.86,P＜0.05).CSW组发现平均尿血钠浓度比与平均尿量的相关系数r=0.79(P＜0.05),个体尿血钠浓度的峰值与病程长短相关.结论尿血渗透压比值能动态反应脑外伤后DI患者机体的相关内分泌状态,并且是判断预后的一个因素.尿血钠浓度比是判断脑外伤后CSW病程长短的一个指标.
- [1]Mabrouk Bahloul,Hedi Chelly,Hichem Ksibi,etc.Prognosis of Traumatic Head Injury in South Tunisia: A Multivariate Analysis of 437 Cases[J].2004,57(2).
- [2]Chad D, Cole,Oren N, Gottfried,James K, Liu,etc.Hyponatremia in the neurosurgical patient: diagnosis and management.[J].2004,16(4).
- [3]Alejandro Rabinstein,Eelco Wijdicks.Hyponatremia in Critically Ill Neurological Patients[J].2003,9(6).
- [4]Deepak, Agrawal,A K, Mahapatra.Pituitary apoplexy and inappropriate ADH secretion.[J].2003,10(2).