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Clearance effect of routine blood purification methods on parathyoid hormone in chronic hemodialysis patients
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF EMERGENCY MEDICINE
- Issue:
- 1
- DOI:
- 10.3760/j.issn:1671-0282.2005.01.016
- Key Word:
- 慢性肾功能衰竭;血液透析;血液透析滤过;血液灌流;甲状旁腺素
Abstract： 目的比较3种常用血液净化方法对维持性血液透析患者血清甲状旁腺素(PTH)的清除效果.方法将90例维持性血液透析患者随机分为3组:血液灌流+血液透析组(HD+HP)、血液透析滤过组(HDF)、血液透析组(HD),HD+HP组接受树脂吸附联合血液透析治疗,HDF组接受血液透析滤过治疗,HD组接受血液透析治疗,放射免疫法测定血清PTH水平.结果(1)HD+HP治疗后患者血PTH从(291.7±237.5)pg/ml降至(122.2±114.5)pg/ml,平均单次清除率为48.6%,治疗前后比较差异有显著性(P＜0.05);(2)HDF治疗后患者血PTH从(325.9±423.1)pg/ml降至(90.9±93.7)pg/ml,平均单次清除率为59.5%,治疗前后比较差异有显著性(P＜0.05);(3)HD治疗后血PTH从(297.7±211.3)pg/ml降至(248.1±105.5)pg/ml,平均单次清除率为13.1%,治疗前后比较差异无显著性(P＞0.05).结论血液灌流联合血液透析和血液透析滤过能有效地清除PTH,两者清除率差异无显著性;而血液透析不能有效地清除PTH.
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