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Evaluation of intraarterial infusion of urokinase in patients with acute ischemic stroke
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- Author:
- No author available
- Journal Title:
- JOURNAL OF EMERGENCY MEDICINE
- Issue:
- 5
- DOI:
- 10.3760/j.issn:1671-0282.2002.05.004
- Key Word:
- 急性脑梗死;溶栓疗法;尿激酶
Abstract： 目的评价动脉内尿激酶溶栓治疗急性脑梗死的结果,并明确影响预后的因素.方法对48例急性颅内动脉闭塞患者在发病6h内进行了局部动脉内尿激酶灌注治疗.结果 48例患者中有17例(35%)获得完全再通,其中13例椎基底动脉阻塞者有8例(62%),20例大脑中动脉阻塞者有9例(45%),而15例颈内动脉阻塞者则无一例完全再通.60%大脑中动脉阻塞者神经状态得到改善,而椎基底动脉与颈内动脉阻塞者分别有39%与20%得到改善(P＜0.05).总的死亡率为21%.结论大脑中动脉阻塞的患者血管完全再通后神经状态可得到改善,而椎基底动脉阻塞者再通与临床改善两者间并无必然联系,颈内动脉阻塞者则很难获得完全再通.
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