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Evaluation of the efficacy of delayed intravenous thrombolytic therapy in elderly patients with acute myocardial infarction
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- Author:
- No author available
- Journal Title:
- JOURNAL OF EMERGENCY MEDICINE
- Issue:
- 3
- DOI:
- 10.3760/j.issn:1671-0282.2002.03.005
- Key Word:
- 心肌梗死;溶栓疗法
Abstract： 目的对63例急性心肌梗死(AMI)发病后6～12h的老年患者进行延迟溶栓治疗的效果进行研究,探讨该时间段的治疗价值及存在问题.方法将经溶栓治疗的AMI患者列为溶栓组,未经溶栓治疗者列为对照组;溶栓组又根据胸痛和ST段抬高情况再分为3个亚组:ST段仍抬高并伴有明显胸痛者(A组);ST段抬高,不伴有明显胸痛者(B组);无明显ST段抬高,但有明显胸痛者(C组);观察溶栓组及亚组梗塞血管再通率,对比分析两组疗效及梗塞后4周内心脏事件发生率、出血发生率.结果 1.溶栓组总的梗塞血管再通率为41.3%,A组、B组和C组则分别为46.4%、28.6%和42.9%;2.溶栓组4周内心脏事件发生率较对照有明显下降(P＜0.01),尤以梗塞后心绞痛发生率减少最为显著(P＜0.01),同时心功能状态有明显改善(P＜0.01);3.出血并发症发生率两组差异无显著意义(P＞0.05).结论对发病后6～12 h AMI患者应积极进行延迟溶栓治疗,尤其对于仍伴有明显胸痛者.
- [1]W E, Boden,W W, Brooks,C H, Conrad,etc.Incomplete, delayed functional recovery late after reperfusion following acute myocardial infarction: "maimed myocardium".[J].1995,130(4).
- [2]王凤昆,黄占东,李景荣.超声心动图对急性心肌梗死延迟溶栓的评价[J].2000,(9).
- [3]D, Massel,J A, Dawdy,L J, Melendez.Strict reliance on a computer algorithm or measurable ST segment criteria may lead to errors in thrombolytic therapy eligibility.[J].2000,140(2).
- [4]Fraser AG,Mumford AD,Owen SJ,etc.Delays by patients in seeking treatment for acute chest pain: implications for achieving earlier thrombolysis.[J].1999,75(880).
- [5]G, Caires,D, Pereira,A D, Freitas,etc.Thrombolytic therapy impact on prognosis after twelve months of first acute myocardial infarction.[J].2000,19(11).