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Experimental investigation of Zhixie recipe on small intestinal motion and absorption

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Author:
No author available
Journal Title:
International Journal of Traditional Chinese Medicine
Issue:
10
DOI:
10.3760/cma.j.issn.1673-4246.2012.10.011
Key Word:
治泻方;小肠运动与吸收;Zhixie recipe;Small intestinal motion and absorption

Abstract: Objective To investigate the effects and mechanism of Zhixie recipe on small intestinal motility of rats and absorption ability of rabbits.Methods Three groups of rats,one was fed with distilled water,the another two were fed with Zhixie recipe liquid of 1 g/ml and 2 g/ml.Then all three groups were fed with ink,and the moving distance of the ink in small intestines was measured to check the small intestinal motility; Three mixtures of Zhixie recipe liquid and desktop solution with 0%,5% and 10% Zhixie recipe liquid were injected into rabbits,the Chloride ion concentration in small intestines was measured to check the absorption ability.Results The average moving distance percentage of ink in the small intestines of the three groups of rats was 52.55% ( SD =8.24),54.35% (SD =12.53 ) and 59.45% ( SD=14.17) of the total intestine length respectively.It showed that Zhixie recipe had no influence on small intestinal motility (P>0.05) ; Small intestines absorption experiments revealed that the small intestinal absorption ability was quite different between the rabbits with desktop solution and the rabbits with mixtures of Zhixie recipe liquid and Desktop solution (5% and 10%),with x2=6.92 and 46.18,P<0.01.The mixtures with 5% and 10% Zhixie recipe liquid improved the small intestinal absorption ability,and the effect of the mixture with 10% was even stronger.Conclusion Zhixie recipe showed no influence on small intestinal motility,but it improved the small intestinal absorption ability.

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