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Microvesicles in immune regulation: an update

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Author:
No author available
Journal Title:
International Journal of Dermatology and Venereology
Issue:
4
DOI:
10.3760/cma.j.issn.1673-4173.2012.04.016
Key Word:
Microvesicles;免疫;免疫耐受;Microvesicles;Immunity;Immune tolerance

Abstract: Microvesicles are membrane-covered cell fragments released by various types of cells during apoptosis or activation.As a way of cellular communication,microvesicles have become the focus of researches in several areas.They may come from various types of cells and body fluids,such as B cells,dendritic cells,platelets,reticulocytes,mononuclear macrophages,serum,urine,amniotic fluid and milk.Current researches in this area are focused on microvesicles released by antigen-presenting cells.Recent studies have shown that microvesicles play important roles in immune regulation.This paper outlines the functions of microvesicles in the induction of immune response and immune suppression.

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