Four cases of nevoid hyperkeratosis of the nipple and areola

( views:171, downloads:0 )
Author:
CHEN Hao(Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China)
LIN Tong(Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China)
JU Mei(Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China)
XU Xiu-lian(Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China)
SUN Jian-fang(Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China)
ZENG Xue-si(Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China)
Journal Title:
International Journal of Dermatology and Venereology
Issue:
Volume 38, Issue 03, 2012
DOI:
10.3760/cma.j.issn.1673-4173.2012.03.001
Key Word:
Nevoid hyperkeratosis of the nipple and areola;Pathological processes;Skin manifestations

Abstract: Objective To report 4 cases of nevoid hyperkeratosis of the nipple and areola.Methods Clinical and histopathological manifestations of 4 cases of nevoid hyperkeratosis of the nipple and areola were observed and retrospectively analyzed.Results Of the 4 patients,1 was male and 3 were female.The average age and disease duration were 32 and 4.5 years respectively.All cases showed hyperkeratosis and verrucous hyperplasia of the nipple and/or areola.Histopathology showed epidermal hyperkeratosis,papillomatous hyperplasia and elongation of the epidermal rete ridges.Conclusions Nevoid hyperkeratosis of the nipple and areola,a subtype of the hyperkeratosis of the nipple and areola,is uncommon in clinic and occurs mainly in young women with characteristic clinical and histological features.

  • [1]Toros P,Onder M,Gürer MA.Bilateral nippl e hyperkeratosis treated successfully with topical isotretinoin.Australas J Dermatol,1999,40(4):220-222.
  • [2]刘艳,王俊民,肖生祥,等.痣样乳头乳晕角化过度症一例.中华皮肤科杂志,2006,39(12):723.
  • [3]Mold DE,Jegasothy BV.Estrogen-induced hyperkeratosis of the nipple.Cutis,1980,26(1):95-96.
  • [4]Vestey JP,Bunney MH.Unilateral hyperkeratosis of the nipple:the response to cryotherapy.Arch Dermatol,1986,122 (12):1360-1361.
  • [5]Kubota Y,Koga T,Nakayama J,et al.Naevoid hyperkeratosis of the nipple and areola in a man.Br J Dermatol,2000,142 (2):382-384.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn