You Position: Home > Paper
miRNAs and dermatoses
( views:197, downloads:60 )
- Author:
- No author available
- Journal Title:
- International Journal of Dermatology and Venereology
- Issue:
- 5
- DOI:
- 10.3760/cma.j.issn.1673-4173.2011.05.019
- Key Word:
- 皮肤疾病;微RNAs;基因表达调控;Skin diseases;microRNAs;Gene expression regulation
Abstract： miRNAs (microRNAs)are a class of small, non-encoding, endogenous RNAs of 21-25 nucleotides (nts) in length. By binding to target mRNAs, they exert various modulatory effects in different species, tissues and diseases. Also, it has been demonstrated that they are associated with some dermatoses and characteristically expressed in these dermatoses. Further investigation into the relationship between miRNAs and skin diseases will provide new ideas and targets for the treatment of diseases.
- [1]Lydia V, McClure,Christopher S, Sullivan.Kaposi's sarcoma herpes virus taps into a host microRNA regulatory network.[J].2008,3(1).
- [2]Candi E,Aberdam D,Melino G,etc.miRNAs, 'stemness' and skin[J].2008,33(12).
- [3]Yi R,Stoffel M,Poy MN,etc.A skin microRNA promotes differentiation by repressing 'stemness'.[J].2008,452(7184).
- [4]Cullen Bryan R..Viral and cellular messenger RNA targets of viral microRNAs[J].2009,457(7228).
- [5]Sonkoly E,Stahle M,Pivarcsi A.MicroRNAs: novel regulators in skin inflammation.[J].2008,33(3).
- [6]Samols, Mark A.,Skalsky, Rebecca L.,Maldonado, Ann M.,etc.Identification of Cellular Genes Targeted by KSHV-Encoded MicroRNAs.[J].2007,3(5).
- [7]Knight RA,Melino G,di-Val-Cervo PR,etc.miR-203 represses 'stemness' by repressing DeltaNp63.[J].2008,15(7).
- [8]Tobias JW,Zhang YH,Seykora JT,etc.The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles[J].2006,16(10).
- [9]Yu, J,Ryan, DG,Getsios, S,etc.MicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epithelia[J].2008,105(49).
- [10]Lu Q,Wang XR,Zhang W,etc.MicroRNA-221 silencing predisposed human bladder cancer cells to undergo apoptosis induced by TRAIL.[J].2010,28(6).
- [11]Lim Lee P.,Lau Nelson C.,Garrett-Engele Philip,etc.Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs[J].2005,433(7027).
- [12]Classen EH,Chen R,Coffey DG,etc.MicroRNA-137 targets microphthalmia-associated transcription factor in melanoma cell lines.[J].2008,68(5).
- [13]Koster, Maranke I.,Kim, Soeun,Mills, Alea A.,etc.p63 is the molecular switch for initiation of an epithelial stratification program.[J].2004,18(2).
- [14]Worley LA,Onken MD,Harbour JW,etc.Micro-RNAs associated with metastasis in uveal melanoma identified by multiplexed microarray profiling.[J].2008,18(3).
- [15]O'Carroll D,Fuchs E,Zhang Z,etc.Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs.[J].2006,38(3).
- [16]Fyhrquist N,Xu N,Janson P,etc.MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4.[J].2010,126(3).
- [17]Sand,D.,Gambichler,T.,Sand,M.,etc.MicroRNAs and the skin: Tiny players in the body's largest organ[J].2009,53(3).
- [18]Yuanjia Tang,Xiaobing Luo,Huijuan Cui,etc.MicroRNA‐146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins[J].2009,60(4).