Application of flow cytometry in mycosis fungoides and Sézary syndrome

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Author:
ZENG Yue-ping(Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China)
WANG Bao-xi()
Journal Title:
INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
Issue:
Volume 36, Issue 05, 2010
DOI:
10.3760/cma.j.issn.1673-4173.2010.05.005
Key Word:
Mycosis fungoides;Sézary syndrome;Flow cytometry;Lymphoma,T-cell;Skin

Abstract: Flow cytometry (FCM) has been more and more widely applied in the researches of cutaneous T-cell lymphoma for its capability to rapidly and simultaneously analyze properties of multiple cells in a quantitative manner. Since FCM could detect abnormal immunophenotypes and monoclonality of neoplastic T cells using antibodies to T-cell superficial antigens and T-cell receptor beta-chain variable region families (TCR-V β), respectively, it has become an important tool for ancillary diagnosis and monitoring of

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