Abstract: A case of desmoplastic trichoepithelioma is reported and relevant literature is reviewed.A 76-year-old female patient complained of erythematous annular plaque on the left upper lip for more than 10 years.The annular plaque measuring 1cm in diameter is firm on palpation with a raised border and smooth surface.Histologically,there was an evident proliferation of collagen fiber in dermis with narrow strands of basaloid cells and epidermoid cysts infiltrating the desmoplastic stroma.