A case of lupus planus

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KANG Yu-ying(Institute of Dermatology,Chinese Academy of Medical Sciences and Peking Union Medical College,Nanjing 210042,China)
ZHANG Lu-lu()
LIN Tong()
WANG Hong-sheng()
ZHANG Cai-ping()
CHEN Hao()
GU Heng()
Journal Title:
Volume 35, Issue 03, 2009
Key Word:
Lupus;Mycobacterium tuberculosis;Diagnosis

Abstract: A 70-year-old woman was admitted for a 2-year-history,pruritic and erythematous patches on the chest and back.Skin examination showed large-sized,infiltrative and red-brown patches,papules,plaques,and some lesions were covered with blood crusts.Histopathologically,there were epithelioid histiocyte masses in the upper and middle dermis,lymphocytic infiltrate were observed around some masses.No fungus was found from clinical specimens by microscopy or culture.Biopsy specimens were positive for an 8-week mycobacterium culture and acid-fast bacilli,and the isolate was identified as Mycobacterium tuberculosis by PCR-restriction fragment length polymorphism(PCR-RFLP)analysis.The case was diagnosed as lupus planus according to clinical manifestation and laboratory tests.

  • [1]Chong LY,L o KK.Cutaneous tuberculosis in Hong Kong:a 10-year retrospective study.Int J Dermatol,1 995,34(1):26-29.
  • [2]雷小兵,工俊,谭升顺,等.寻常狼疮16例误诊分析.中国皮肤性病学杂志,2004,18(12):757-759.
  • [3]Garcia-Rodroguez JF,Monteagudo-Sanchez B,Marifio-Callejo A.Cutaneous tuberculosis:a 15-year descriptive study.Enferm Infecc Microbiol Clin,2008,26(4):205-211.
  • [4]Ho CK,Ho MH,Chong LY.Cutaneous tuberculosis in Hong Kong:an update.Hong Kong Med J,2006,12(4):272-277.
  • [5]Hsiao PF,Tzen CY,Chen HC,et al.Polymerase chain reaction based detection of Mycobacterium tuberculosis in tissues showing granulomatous inflammation without demonstrable acid-fast bacilli.Int J Dermatol,2003,42(4):281-286.
  • [6]Vaneechoutte M,De Beenhouwer H,Claeys G,et al.Identification of Mycobactefium species by using amplified ribosomal DNA restriction analysis.J Clin Microbiol,1993,31(8):2061-2065.
  • [7]Brunello F,Ligozzi M,Cristelli E,et al.Identification of 54 mycobacterial species by PCR-restriction fragment length polymorphism analysis of the hsp65 gene.J Clin Microbiol,2001,39(8):2799-2806.
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