A case of lupus planus

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Author:
KANG Yu-ying(Institute of Dermatology,Chinese Academy of Medical Sciences and Peking Union Medical College,Nanjing 210042,China)
ZHANG Lu-lu()
LIN Tong()
WANG Hong-sheng()
ZHANG Cai-ping()
CHEN Hao()
GU Heng()
Journal Title:
INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
Issue:
Volume 35, Issue 03, 2009
DOI:
10.3760/cma.j.issn.1673-4173.2009.03.004
Key Word:
Lupus;Mycobacterium tuberculosis;Diagnosis

Abstract: A 70-year-old woman was admitted for a 2-year-history,pruritic and erythematous patches on the chest and back.Skin examination showed large-sized,infiltrative and red-brown patches,papules,plaques,and some lesions were covered with blood crusts.Histopathologically,there were epithelioid histiocyte masses in the upper and middle dermis,lymphocytic infiltrate were observed around some masses.No fungus was found from clinical specimens by microscopy or culture.Biopsy specimens were positive for an 8-week mycobacterium culture and acid-fast bacilli,and the isolate was identified as Mycobacterium tuberculosis by PCR-restriction fragment length polymorphism(PCR-RFLP)analysis.The case was diagnosed as lupus planus according to clinical manifestation and laboratory tests.

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