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A case of follicular mucinosis progressing into mycosis fungoides
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- Author:
- No author available
- Journal Title:
- INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.1673-4173.2008.02.001
- Key Word:
- 黏蛋白累积病,毛囊皮脂腺;蕈样肉芽肿;秃发
Abstract： 患者男,36岁,躯干四肢泛发毛囊性丘疹、斑片及浸润性斑块伴瘙痒15年余,头面部结节性浸润性肿块伴脱发3个月.发病后第13年无明确的与恶性淋巴瘤相关的临床及组织学证据.发病后第15年组织活检见真皮内及毛囊周围单个核细胞团块状浸润或在胶原束间穿插,部分细胞核大深染,有异形性,并见单个核细胞移入毛囊,部分毛囊上皮水肿破坏、甚至形成囊腔结构,其中充满黏蛋白.阿新蓝染色阳性.免疫组化示:CD45RO++,CD20-,CD4++++,CD8-.该患者在诊断为毛囊黏蛋白病15年后发现合并蕈样肉芽肿.
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