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Relationship between acquired hemophilia A and some cutaneous disorders

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Author:: No author available

Journal Title:: INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY

Issue:: 4

DOI:: 10.3760/cma.j.issn.1673-4173.2007.04.005

Key Word:: 血友病A;因子Ⅷ;皮肤疾病

Abstract：获得性血友病A是一类后天获得的凝血因子8缺乏性疾病,某些皮肤病如大疱性疾病、银屑病、系统性红斑狼疮、蕈样肉芽肿等可伴发获得性血友病A.患者可出现皮肤及其他各器官的出血,实验室检查活化的部分凝血活酶时间延长,第8因子活性降低.获得性血友病A与这些皮肤病合并的机制可能与免疫紊乱有关.可系统应用糖皮质激素、免疫抑制剂及凝血因子等治疗.

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