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Acitretin in the Treatment of Cutaneous Disorders of Keratinization in Children
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- Author:
- No author available
- Journal Title:
- INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1673-4173.2006.03.002
- Key Word:
- 阿维A;角化;儿童
Abstract： 阿维A为第二代维A酸,是阿维A酯的代谢活性酸,具有较高的生物利用度及较短的半衰期,已广泛治疗各种角化性皮肤病,而这些角化性疾病大多是遗传性疾病.这些疾病主要见于儿童和青少年,因此,阿维A与儿童和青少年角化性疾病有着重要的联系,但阿维A除治疗作用外,该类药物对人类从妊娠到儿童的肝脏、骨骼生长及生殖系统等亦有一定的潜在不良影响,又因为用药经验不足,造成用药时有所顾虑,特别是国内对其在儿童角化性疾病的研究不多.
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