Abstract： Objectives To evaluate the clinical efficacy of combined therapy with tansuoluoxin and solifenacin for patients with benign prostatic hyperplasia.Methods 52 patients with benign prostatic hyperplasia without serious obstructive symptom were randomly assigned to two groups.28 patients are observation group,treated with tansuoluoxin and solifenacin.24 patients are contorl group,treated with tansuoluoxin only; after ten weeks of treatment,compere the before and after difference of the measured indicators.And the difference in determination of indicators after treatment.Results Ten weeks after treatment,the IPSS,score on the urinary storage phase symptoms,residual urine volume,number of micturation per 24h,number of incontinence per 24h and number of enuresis nocturna significantly decreased in tansuoluoxin group( P ＜0.05 ),while maximum urinary flow rate and mean voiding volume significantly increased( P ＜0.05 ).There were significant differences in IPSS,score on the urinary storage phase symptoms,number of incontinence and number of enuresis nocturna between two groups after treatment (P ＜0.05).Conclusions Transurethral ureteroscopic treatment of hemospermia is an effective way,there are less postoperative complications,it has a good clinical value.