Abstract: Objective To observe the clinical effect of unusual arteriovenous fistula in maintenance hemodialysis patients.Methods Hemodialysis nursing characteristics and nursing management for 60 patients with unusal hemodialysis arteriovenous fistula were analyzed retroactively and nursing experience were summarized. Results After establishment of unusual arteriovenous fistula of 60 cases of patients vascular patency rate was 100%,40 cases started using after 3 months of postoperative,11 cases after 5 months and 9 cases after 6 ~ 8 months,lasting use over 2 ~ 3 years,all of cases had no infection and blocking.Conclusions Unusual arteriovenous fistula is a additional way of patients with permanent hemodialysis vascular access,careful care is the key to extend the service life.