Abstract: Objective To investigate the effect of evidence -based nursing used in the high -quality nursing service in operation room. Methods A total of 400 patients was randomly divided into evidence - based nursing group ( EBN group) and control group ( n =200 ).The EBN group adopted the evidence - based nursing via visiting prior to surgery,nursing during surgery and follow - up post surgery.In control group,the patients were treated with routine nursing.Results The patients in EBN group showed better outcome in perioperative psychology,comfortable degree in operation,occurrence of complications,and satisfaction than outcome of patients in control group ( P < 0.01 ).Conclusions The evidence - based nursing can improve the quality of nursing in operation room,improve the patients' satisfaction,reduce the perioperative complications,accelerate the patients' recover and strengthen the nursing quality.