Abstract： Objective To investigate effectiveness of database management to improve the quality of care in the childhood asthma. Methods A database was established on extensive data which were collected from different regions and different age children with asthma of the Childhood Asthma Center of Boai Hospital in Zhongshan City. The patients were called and visited regularly according to the database, then, supervised their rational medication and performed health education. The program had been running for two years. The social benefit and treatment quality were compared with specialized paper medical record management. Results Database standardized management saved considerable time retrieval of information. Clinical controlling ratio, subsequent visit regularly and parent's satifactions were improved noticeably. Children were less to be readmitted to the hospital Conclusions The database management can increase rates of return visit and clinical controlling, and lower recrudescent rate of asthma Consequently, it is worth being further popularized.