Abstract： Objective To study the related factors on the abnormal results of LCT combined with HPV test on the out -patients and physical examination crowd. Methods The out -patients and medical examination combined screening women 10000 cases were randomly selected. General information on the questionnaire, gynecological comprehensive assessment tables related factors were investigated. Results Out -patients opportunistic screening: (LCT) exception was 15. 9%, HPV infection -positive rate was 29%, both exception 1 308 patients ( 13.08% ); personsreceived screening: (LCT) exception rate was 10. 9%, HPV infection -positive rate was 13%, both exception 916 patients (9. 16% ); the two types of people had abnormal results compared statistically (P ＜0. 05). Sex age early, multiple personality partner or partner had multiple personality partner, many pregnant prolific, socio-economic status, a variety of microbial infection etc predisposing factors in outpatient populations reflect were significantly higher than those in the physical examination population. Conclusions Cervical cancer -related risk factors for out -patients population are significantly higher than those in the physical examination crowd. The health care workers should adopt different health education basis on different out -patient crowd, preventing and discovering cervical precancerous lesions, to achieve the prevention and elimination of HPV infection, earlier finding, earlier treatment.