Abstract： Objective To explore the present status of occupational stress and job burnout in Shantou medical personnel, and compare their relationship. Methods Medical personnel in seven hospitals of Shantou city were enrolled. A well - rounded measurement of occupational stress and job burnout in medical personnel by translating was made. Analysis of variance was employed to analyze the marks of each sub -project in the inventory. Therefore, the present status and their relationship of occupational stress and job burnout were explored in Shantou medical personnel Results Five hundred and seventy - six in 600 questionnaires by stochastic processes were received in seven hospitals of Shantou city, 540 of them were available, and the effective power was 90%. The results manifested that occupational stress and job burnout were both severe in medical personnel, more occupational stress in physician than that in nurse, and more severe of job burnout in clinical staff and that in rear - service personnel. Conclusions The present study could provide scientific basis for further intervention to relieve workload, elevate efficiency, protect and promote physical and mental health among medical personnel, and also advance doctor - patient relationship and medical development.