You Position: Home > Paper
Morphological evidence of axoplasm flow resumed regenerative nerve fiber after end-to-side neurorrhaphy
( views:184, downloads:1 )
- Author:
- No author available
- Journal Title:
- JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY
- Issue:
- 17
- DOI:
- 10.3321/j.issn:1000-2790.2002.17.002
- Key Word:
- 端侧神经吻合;神经再生;轴浆流
Abstract： 目的观察神经轴浆流恢复情况,进一步证实端侧神经吻合后纤维再生的可能性. 方法用新西兰兔进行研究,随机分为A,B两组. A组:实验组将左侧耳大神经切断吻合于右侧耳大神经干上;B组:对照组仅切断神经. 术后2,4,6,8和12 wk,将HRP注入吻合口远端的受神经内,动物再存活4 d,免疫组化法观察C1-C3背根神经节内的标记阳性细胞. 结果供神经的新生轴突能通过吻合口长入受神经,随时间的延长,神经节内的阳性细胞的数量不断增加. 结论端侧神经吻合后侧支发芽再生,且恢复了一定的功能.
- [1]李跃军,陈绍宗,程飙,等.端侧神经吻合口轴突再生的形态学依据[J].1999,(2).
- [2]曹祖峰,陈绍宗,张盈华,等.兔耳大神经端侧吻合后神经元胞体和神经干内cAMP的水平[J].1999,(11).
- [3]曲辉,陈绍宗,刘明锁,等.兔神经端侧吻合再生轴突荧光素双标记研究[J].2000,(12).
- [4]Brunelli F,Lacroix C,Papalia I,etc.Direct muscle neurotization after end-to-side neurorrhaphy.[J].2001,17(4).
- [5]Terzis JK,Okajima S.Ultrastructure of early axonal regeneration in an end-to-side neurorrhaphy model.[J].2000,16(4).
- [6]Haughey BH,Hunter DA,Watanabe O,etc.End-to-side neurorraphy: a long-term study of neural regeneration in a rat model.[J].1998,119(4).
- [7]Beris AE,Ioachim E,Agnantis NJ,etc.Reinnervation after end-to-side nerve coaptation in a rat model.[J].2001,30(5).
- [8]T, Yamauchi,M, Maeda,S, Tamai,etc.Collateral sprouting mechanism after end-to-side nerve repair in the rat.[J].2000,33(3).
- [9]Yuksel F,Karacaoglu E,Guler MM.Nerve regeneration through side-to-side neurorrhaphy sites in a rat model: a new concept in peripheral nerve surgery.[J].1999,104(7).
- [10]Urbaniak JR,Rowan PR,Chen LE.End-to-side nerve repair. A review.[J].2000,16(1).