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Investigation progress for cerebral ischemia pretreatment
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- Author:
- No author available
- Journal Title:
- JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY
- Issue:
- 15
- DOI:
- 10.3321/j.issn:1000-2790.2002.15.002
- Key Word:
- 脑缺血;预处理;发展
Abstract： @@ 0 引言缺血预处理和缺血耐受现象最早是由Murry等于1986年在犬心肌缺血模型中发现的. 1990年Kitagawa等证实该现象同样存在于大脑,随后更多的实验证实了缺血耐受现象的器官普遍性[1]. 缺血耐受现象即事先给予一亚致死性的脑缺血(缺血预处理),可减轻其后发生的致死性脑缺血带来的损害. 随着研究的深入,脑缺血预处理的概念逐渐拓展,预处理的方法不再仅限于脑缺血,而是涵盖了许多"亚毒性"的侵害性物质或措施. 有关预处理机制的研究也是当前的热点之一.
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