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Clinical role of experimental transcatheter closure of PDA by Amplatzer occluder device in the closure of PDA with severe pulmonary hypertension
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- Author:
- No author available
- Journal Title:
- JOURNAL OF THE FOURTH MILTARY MEDICAL UNIVERSITY
- Issue:
- 21
- DOI:
- 10.3321/j.issn:1000-2790.2001.21.002
- Key Word:
- 动脉导管未闭;Amplatzer封堵器;肺动脉高压
Abstract： 目的 Amplatzer封堵器试验性关闭动脉导管未闭(PDA),评价其在PDA合并重度肺动脉高压(SPH)患者封堵治疗中的临床价值. 方法对7(男4,女3)例PDA合并SPH患者实施PDA封堵器堵塞PDA试验,观察肺动脉收缩压、肺动脉平均压有无降低及血氧饱和度变化,以此分析肺血管病变是否可逆. 结果 7例重度肺动脉高压者,肺动脉收缩压11.3～18.7 (12.8±4.9) kPa,平均压为6.9～12.3 (9.1±2.5) kPa,其中2例血氧饱和度小于90%, 6例试封堵术后30 min～1 h肺动脉收缩压降至6.0～13.1 (7.6±3.1) kPa,肺动脉平均压降至2.7～8.3 (4.4±2.8) kPa,行永久性封堵治疗. 1例肺动脉压和动脉血氧饱和度无明显变化,为阻力性肺动脉高压,不宜进行封堵治疗. 结论对于PDA伴严重肺动脉高压者,Amplatzer封堵器关闭PDA试验是鉴别肺动脉高压是否为阻力性肺动脉高压的安全有效的方法,在Amplatzer法封堵器治疗PDA合并重度肺动脉高压(SPH)的病例选择中有重要的临床价值.
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