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Computer-aided three-dimensional reconstruction of the striatum, marginal division and globus pallidus in an adult rat brain
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- Author:
- No author available
- Journal Title:
- JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY
- Issue:
- 8
- DOI:
- 10.3321/j.issn:1000-2790.2000.08.005
- Key Word:
- 纹状体;边缘区;尾壳核;苍白球;计算机;三维重建
Abstract： 目的建立和了解成年大鼠纹状体、边缘区和苍白球在脑中的立体形态和相互关系.方法在大鼠脑的连续冠状切片Nissl染色的基础上通过Onyx2超级图形工作站应用计算机图形技术进行了三维重建.结果边缘区位于尾壳核和苍白球之间;尾壳核的立体形态呈近似的内凹半球形,从嘴侧到尾侧随着脑平面的增宽尾壳核逐渐向外侧(即靠近外轮廓的方向)移位,体积为(37.77±9)mm3,最大嘴尾径为6.2mm;最大背腹径为4.9mm;最大内外径为3.529mm.苍白球呈块形,位于尾壳核的内侧,除内侧外其他三个方向均被尾壳核包绕,体积为(4.05±0.06)mm3,最大嘴尾径为4.41mm,最大背腹径为2.645mm,最大内外径为1.544mm.边缘区呈现一个片状扇形结构,体积为(0.48±0.02)mm3,最大嘴尾径为1.6mm,最大背腹径为2.158mm,最大内外径为0.17mm;同尾壳核和苍白球一样从嘴侧到尾侧随着脑平面的增宽边缘区亦逐渐向外侧(即靠近外轮廓的方向)移位,其移位的幅度亦明显大于脑平面增宽的幅度;整个边缘区从嘴侧到尾侧呈均匀变化,其片状逐渐变宽,长度(背腹径)逐渐变小,从而形成一个盘状结构.结论建立了大鼠脑纹状体、边缘区和苍白球的三维立体结构.
- [1]A W, Toga,E M, Santori,R, Hazani,etc.A 3D digital map of rat brain.[J].1995,38(1).
- [2]S A, Bayer,X, Zhang,R J, Russo,etc.Three-dimensional reconstructions of the developing forebrain in rat embryos.[J].1994,1(4).
- [3]Manley, M. S.,Young, S. J.,Groves, P. M..Compartmental organization of the peptide network in the human caudate nucleus[J].1994,7(3).
- [4]P, Rakic,L J, Stensas,E, Sayre,etc.Computer-aided three-dimensional reconstruction and quantitative analysis of cells from serial electron microscopic montages of foetal monkey brain.[J].1974,250(461).
- [5]S A, Scott,S T, DeKosky,S W, Scheff.Volumetric atrophy of the amygdala in Alzheimer's disease: quantitative serial reconstruction.[J].1991,41(3).
- [6]Mailly P,Roesch S,Maurin Y,etc.Computer assisted three-dimensional reconstruction of brain regions from serial section digitized images. Application to the organization of striato-nigral relationships in the rat.[J].1996,69(2).
- [7]M E, Martone,S J, Young,D M, Armstrong,etc.The distribution of cholinergic perikarya with respect to enkephalin-rich patches in the caudate nucleus of the adult cat.[J].1994,8(1).
- [8]S.Y. Shu,J.F. McGinty,G.M. Peterson.High density of zinc-containing and dynorphin B- and substance P-immunoreactive terminals in the marginal division of the rat striatum[J].1990,24(2).
- [9]T S, Ford-Holevinski,M R, Castle,J P, Herman,etc.Microcomputer-based three-dimensional reconstruction of in situ hybridization autoradiographs.[J].1900,4.
- [10]M. Gerke,H. Vogt,W. Fiekert,etc.3D reconstructions of neurofunctional structures for neuroimaging[J].1996,20(1).
- [11]J S, Schwaber,W T, Rogers,K, Satoh,etc.Distribution and organization of cholinergic neurons in the rat forebrain demonstrated by computer-aided data acquisition and three-dimensional reconstruction.[J].1987,263(3).