Correlation of changes in cerebral deep vein and internal jugular vein with multiple sclerosis
- Author:
- No author available
- Journal Title:
- Acta Academiae Medicinae Militaris Tertiae
- Issue:
- 19
- DOI:
- No doi available
- Key Word:
- 多发性硬化;磁共振成像;脑深部静脉;颈内静脉
Abstract： 目的 探讨脑内深部髓质静脉(deep medullary veins,DMVs)特征表现和颈内静脉(internal jugular veins,IJVs)改变与多发性硬化(multiple sclerosis,MS)的关系.方法 对30例复发缓解型MS患者和30例年龄、性别匹配的非MS对照组行常规磁共振成像(magnetic resonance imaging,MRI)、三维增强T2*加权血管成像(3-dimensional enhanced T2*-weighted angiography,3-D ESWAN)和3-D时间分辨率对比剂动力成像(time-resolved imaging of contrast kinetics,TRICKs)扫描.观察患者和对照组侧脑室体旁DMVs在3-D ESWAN改变并评分；比较患者与对照组DMVs评分和IJVs狭窄发生率的差异,并评价DMVs和IJVs改变分别与EDSS评分和病程的相关性.结果 ①MS患者DMVs评分(1.67±0.25)较对照组(3.00±0.00)显著降低(P＜0.01)；16例病程＞2.0年者为1分,8例病程0.5 ～2.0年者为2分,二者与对照组比较差异均有统计学意义(P＜0.01),6例病程＜0.5年者与对照组比较差异无显著性(P＞0.05).9个慢性病灶“穿通静脉”扩张和延长.②5例(16.7％)MS患者和2例(6.7％)对照组患者IJVs狭窄,2组IJVs狭窄发生率差异无统计学意义(P＞0.05).③IJVs狭窄与DMVs减少无显著相关性(P＞0.05).④DMVs减少、变短与患者病程呈显著负相关(r=-0.89,P＜0.01),与EDSS评分无显著相关性(r=0.05,P＞0.05)；IJVs狭窄与EDSS评分和病程均无显著相关性(Z=0.20,P＞0.05；Z=3.46,P＜0.05).结论 MS患者DMVs改变与IJVs狭窄无显著相关性.
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