Current study status of radiotherapy modality on early stage nasal NK/T cell lymphoma

( views:440, downloads:0 )
HAN Bao-lin(Department of Radiation Oncology, Tianjin Baodi Hospital, Tianjin 301800, China)
Journal Title:
Journal of Leukemia & Lymphoma
Volume 21, Issue 10, 2012
Key Word:
Lymphoma,Non-Hodgkin;Nasal Cavity;Radiation target;Radiation dose;Preventive neck radiation

Abstract: Nasal NK/T cell lymphoma is a rare and distinct type of extranodal Non-Hodgkin' s lymphoma. Current study has proved that Radiotherapy is the most effective treatment method in the early stage nasal NK/T cell lymphoma, but there is no universal standard for concrete radiotherapy modality, such as the radiation target, the radiation dose and preventive neck radiation. Most studies have proved that radiotherapy of extended field and higher dose achieved good effect in early stage nasal NK/T cell lymphoma.And the studies also do not suggested preventive neck radiation in local stage patients, but it need further study in the extensive stage patients.

  • [1]Chan JK. The new World Health Organization classification of the lymphomas:the past,the present and the future.Hematol Oncol,2001,19:129-150.
  • [2]任涛,谭榜宪,柳弥,等.鼻腔自然杀伤/T细胞淋巴瘤放射治疗的疗效和影响因素.白血病·淋巴瘤,2011,20:165-167.
  • [3]韩宝林,庞青松,庞得全,等.四种方法治疗鼻腔非霍奇金淋巴瘤的疗效比较.肿瘤研究与临床,2006,18:177-179.
  • [4]Li YX,Fang H,Liu QF,et al.Clinical features and treatment outcome of nasal-type NK/T-cell lymphoma of Waldeyer ring.Blood,2008,20:619-625.
  • [5]张嵘,谢传淼,莫运仙,等.鼻咽非霍奇金淋巴瘤的MRI表现与侵犯特点.中华放射学杂志,2011,45:170-173.
  • [6]Isobe K, Uno T, Tamaru J, et al. Extranodal natural killer/T-cell lymphoma,nasal type:the significance of radiotherapeutic Parameters.Cancer,2006,106:609-615.
  • [7]阮寒光,邬蒙.鼻腔NK/T细胞淋巴瘤60例临床治疗和预后分析.实用癌症杂志,2009,24:291-294.
  • [8]Kim SJ,Oh SY,Hong JY,et al.When do we need central nervous system prophylaxis in patients with extranodal NK/T cell lymphoma,nasal type? Ann Oncol,2010,21:1058-1063.
  • [9]Kim SJ,Kim K,Kim BS,et al.Phase Ⅱ trial of concurrent radiation and weekly cisplatin followed by VIPD chemotherapy in newly diagnosed,stage Ⅰ E to Ⅱ E,nasal extranodal NK/T cell lymphoma:consortium for improving survival of lymphcma study. J Clin Oncol,2009,27:6027-6032.
  • [10]Wang B,Liu JJ,Ma X,et al.Combined chemotherapy and external beam radiation for stage Ⅰ E and Ⅱ E natural killer T-cell lymphoma of nasal cavity.Leuk Lymph,2007,48:396-402.
  • [11]Wu X, Li P, Zhao J, et al. A clinical study of 115 patients with extranodal natural killer/T-cell lymphoma, nasal type. Clin Oncol,2008,20:619-625.
  • [12]聂大红,谢方云,李济时,等.早期鼻腔NK/T细胞淋巴瘤治疗方法和预后分析.中国放射肿瘤学杂志,2010,19:315-319.
  • [13]Huang MJ,Jiang Y,Liu WP,et al. Early of up-front radiotherapy improved survival of localized extranodal NK/T-cell lymphoma, nasal type in the upper acrodigestive tract.Int J Rad Oncol Biol Phys,2008,70:166-174.
  • [14]刘清峰,李晔雄,吴润叶,等.早期鼻腔NK/T细胞淋巴瘤局部侵犯特点和靶区定义.中华放射肿瘤学杂志,2011,20:301-306.
  • [15]邹丽芬,程庆芳.鼻腔非霍奇金淋巴瘤的治疗.复旦学报:医学科学版,2001,28:363-365.
  • [16]沈倩文,潘自强,郭晔,等.Ⅰ-Ⅱ期鼻腔结外NK/T细胞淋巴瘤放射治疗疗效分析.肿瘤,2011,31:835-840.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615