Research progress on microRNA in pediatric B-cell lymphoblastic leukemia and lymphoma

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Author:
ZHANG Dong-guang(Department of Endocrinology, Jiangxi Children 's Hospital,Nanchang 330006, China)
Journal Title:
Journal of Leukemia & Lymphoma
Issue:
Volume 21, Issue 10, 2012
DOI:
10.3760/cma.j.issn.1009-9921.2012.10.020
Key Word:
MicroRNAs;Leukemia;Lymphoma

Abstract: microRNA (miRNA) is a recently discovered class of new noncoding small RNA molecules,they play key regulatory roles in the genesis,development and prognosis of lymphatic and hematopoietic tumours.This review presents the update on miRNA biogenesis,functionary mechanism and their.role in pediatric B-cell lymphoblastic leukemia and lymphoma.

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