Abstract: Anemia is one of the most common complication and a negative prognostic factor of lymphoid neoplasma. Different cases with lymphoid neoplasma associated anemia (LNAA) have various pathogenesis such as hemorrhagic anemia, anemia of chronic disease, autoimmune hemolytic anemia and treatment related anemia, though they all have the same symptoms. So different regimens are given to different patients according to their pathogenesis of LNAA.