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Advances in biological prognostic indicators of chronic lymphocytic leukemia

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Author:: No author available

Journal Title:: JOURNAL OF LEUKEMIA & LYMPHOMA

Issue:: 1

DOI:: 10.3760/cma.j.issn.1009-9921.2010.01.023

Key Word:: 白血病;淋巴细胞;预后;生物学;Leukemia,lymphocytic;Prognosis;Biology

Abstract： The patients of chronic lymphocytic leukemia(CLL)have great individual differences.It is important for clinicians to determine the prognosis at the beginning of diagnosis and choose proper treatment for the patients.The recent advances in biological prognostic indicators of CLL were reviewed,including IgVH gene mutation status,ZAP70,CD_(38),chromosome abnormality[t(11q;v),del(11q),del(17p),+12 and del(13q)].telomere and telomerase.

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