Classification of cell death and its significance

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Author:
WU Ke-fu(State Key Laboratory for Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China)
ZHENG Guo-guang(State Key Laboratory for Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China)
MA Xiao-tong(State Key Laboratory for Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China)
SONG Yu-hua(State Key Laboratory for Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China)
Journal Title:
JOURNAL OF LEUKEMIA & LYMPHOMA
Issue:
Volume 19, Issue 01, 2010
DOI:
10.3760/cma.j.issn.1009-9921.2010.01.001
Key Word:
Cell death; Cell apoptosis; Necrosis; Autophagy

Abstract: Cell death as the partner of cell proliferation is one of the basic mechanism in cell biology. Recently, it became obscure since more and more patterns of cell death were reported. However, the "classification of cell death", which was recommended by the Nomenclature Committee on Cell Death (NCCD) in 2009, clarified the criteria. The theme of the recommendation and recent data from the literature were discussed in this review. The significance of studies on cell death was discussed.

  • [1]Kroemer G,Galluzzi L,Vandenabeele P,et al.Classification of cell death:recommendations of the nomenclature committee of cell death 2009.Cell Death Diffe,2009,16:3-11
  • [2]宋玉华.细胞凋亡与疾病//吴克复.细胞通讯与疾病:第十二章.北京:科学出版社,2006:353-394.
  • [3]Hitomi J,Christofferson DE,Ng A,et al.Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway.Cell,2008,135:1311-1323.
  • [4]Galluzzi L,Kroemer G.Necroptosis:a specialized pathway of programmed necrosis.Cell,2008,135:1161-1163.
  • [5]吴克复,宋玉华.程序性细胞死亡和细胞衰退的细胞生态学意义//吴克复.肿瘤微环境与细胞生态学导论.北京:科学出版社,2009:9-16,37-39.
  • [6]Dethlefsen L,McFall-Ngai M,Relman DA.An ecological and evolutionary perspective on human-microbe mutualism and disease.Nature,2007,449:811-819.
  • [7]吴克复,马小彤,宋玉华.期望肿瘤细胞凋亡还是坏死?中国实验血液学杂志,2005,13:921-923.
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