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Prognostic significance of the marrow blast decline index in AML (not APL) at the first inductive treatment for 7-10 days

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Author:
No author available
Journal Title:
JOURNAL OF LEUKEMIA & LYMPHOMA
Issue:
12
DOI:
10.3760/cma.j.issn.1009-9921.2009.12.011
Key Word:
白血病;粒细胞;急性;预后;Leukemia;myeloeytic;acute;Prognosis

Abstract: Objective To investigate relationship of the marrow blast decline index(MBDI)in AML (not APL)at the first inductive treatment for 7-10 days and the prognosis.Methods 109 cases of AML were retrospectively analyzed(not APL),to compare theⅡmarrow blast decline index in AML(not APL)at the first inductive treatment for 7-10 days in the continue relieve group,the relapse group and the non-remission group,analyzed the correlation of the MBDI and continue relapse rate,the MBDI and relapse rate.Results The MBDI mean value is 0.8856 in continue relieve group.significantly higher than that of the relapse group (mean=0.4445)and the non-remission group(mean=0.3903)(P<0.0001).The MBDl positively correlated with continue relapse rate(P<0.01);negatively correlated with relapse rate(P<0.01).Conclusion The marrow blast decline index in AML(not APL) at the first inductive treatment for 7-10 days was significant for early assesment ofthe prognosis.

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