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Expression of CD30 in Hodgkin lymphoma cells transfected with mtr Ⅱ gene
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- Author:
- No author available
- Journal Title:
- JOURNAL OF LEUKEMIA & LYMPHOMA
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1009-9921.2009.03.001
- Key Word:
- mtrⅡ基因;霍奇金淋巴瘤;抗原;CD30;Mtr Ⅱ gene;Hodgkin lymphoma;Antigens,CD30
Abstract： Objective To approach the expression and significance of CD30 in Hodgkin lymphoma cells which were transfected with mtr Ⅱ gene. Methods The CD30 expression of Hodgkin lymphoma cells in those transfected with mtr Ⅱ gene was analysed by immunohistochemical technique respectively. Results The CD30 expression rate of Hodgkin lymphoma cells which were transfected with mtr Ⅱ gene was higher than that of Hodgkin lymphoma cells which weren't transfected with mtrⅡ gene (P ＜0.01). Conclusion The mtr Ⅱ gene may be related to the malignant transformation of Hodgkin lymphoma.
- [1]王星,林雨冬,王明元,等.霍奇金淋巴瘤转染mtrⅡ基因后增生细胞核抗原表达的意义[J].2008,(1).
- [2]吕蓉,陈江华.CD30的功能与应用[J].2004,(2).
- [3]王星,林雨冬,王明元,等.转染mtrⅡ基因后霍奇金病细胞增殖活性改变[J].2007,(5).
- [4]Doniger J,Muralidhar S,Rosenthal LJ.Human cytomegalovirus and human herpesvirus 6 genes that transform and transactivate.[J].1999,12(3).
- [5]A, Razzaque,N, Jahan,D, McWeeney,etc.Localization and DNA sequence analysis of the transforming domain (mtrII) of human cytomegalovirus.[J].1988,85.
- [6]萨姆布鲁.分子克隆实验指南[M].1999.