Effect of siRNA on the proliferation in HL-60 cells of leukemic cell line

( views:, downloads: )
SUN Ling()
ZHAO Xiao-qiang()
YUE Bao-hong()
CHEN Yan-li()
LIU Xiao-zhuan()
Journal Title:
Volume 15, Issue 04, 2006
Key Word:


  • [1]Resnitzky D,Kimchi A.Dregulated c-myc expression abrogates the interferon and interleukin 6-mediated G0/G1 cell cycle arrest but not other inhibitory responses in M1 myeloblastic cells[J].Cell Growth Differ,1991,2(1):33-41.
  • [2]Aldo B,Constance M,Cultraro,et al.c-myc inactivation by mutant Max alters growth and morphology of NCI-H-630 colon cancer cells[J].Cell Physiol,1996,169(3):200-206.
  • [3]王松梅,单易非,高红阳,等.反义寡核苷酸对HL-60细胞c-myc基因表达的抑制和诱导分化作用[J].上海医科大学学报,1998,25(3):167-170.
  • [4]Wickstrom E L,Bacon T A,Gomalez A,et al.Human promyelolytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by antisense pen-tadecadeoxynucleotides targeted against c-myc mRNA[J].PNAS USA,1988,85(4):1028-1032.
  • [5]毕慧,王亚军,何琴.急性白血病细胞c-myc基因表达的研究[J].白血病·淋巴瘤,2003,12(2):73-75.
  • [6]Elbashir S M,Lendeckel W,Tuschl T.RNA interference is me2diated by 212 and 222 nucleotide RNAs[J].Genes Dev,2001,15(2):188-200.
  • [7]Sharp P A.RNA interference-2001[J].Genes Dev,2001,15(5):485-490.
  • [8]Elbashir S M,Harborth J,Lendeckel W,et al.Duplexes of 21-nucleotide RNAs mediate RNA interference in culturemammalian cells[J].Nature,2001,411(6836):494-498.
  • [9]曾嵘.c-myc的基因调节作用[J].国外医学遗传学分册,1997,20(2):64-66.
  • [10]Wang Y H,Liu S,Zhang G,et al.Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo[J].Breast Cancer Res,2005,7(2):220-228.
  • [11]Sumimoto H,Yamagata S,Shimizu,et al.Gene therapy for human small-cell lung carcinoma by inactivation of Skp-2 with virally mediated RNA interference[J].Gene Ther,2005,12(1):95-100.
  • [12]Yang D,Lu H,Erickson J W.Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation duringRNAi in drosophila embryos[J].Curr Biol,2000,10(19):1191-1200.
  • [13]Borkhardt A.Blocking oncogenes in malignant cells by RNA interference:new hope for a highly,specific cancer treatment[J].Cancer Cells,2002,2(3):167-168.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn