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CLINICAL SIGNIFICANCE OF ACUTE LEUKEMIA WITH CD56 POSITIVE
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- Author:
- No author available
- Journal Title:
- JOURNAL OF LEUKEMIA & LYMPHOMA
- Issue:
- 5
- DOI:
- 10.3760/cma.j.issn.1009-9921.2001.05.003
- Key Word:
- 急性白血病;CD56;流式细胞仪
Abstract： 目的:探讨CDs6在急性白血病中的表达及其临床意义.方法:就近2年来应用流式细胞仪检测了CD56的92例急性白血患者中发现的CD56阳性病例,分析细胞形态学、免疫表型和临床特点.结果:92例急性白血病中15例(16.3%)表达CD56,其中1例急性前髓系/NK细胞白血病(Myeloid/NK cell precursor acute leukemia),1例原始NK细胞白血病(Blastic NK cell leukemia),1例NK样T细胞淋巴瘤/白血病(NK-like T-cell lymphoma/leukemia),12例急性髓细胞白血病伴NK细胞抗原表达或急性髓系/NK细胞白血病.结论:伴CD56阳性急性白血病,其细胞形态学、免疫表型及临床表现各有特点,见于M2、M5、L2,髓外浸润多见,多预后不良.
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