Abstract： Dear Editor,Bovine coronavirus(BCoV)is a member of the species Betacoronavirus 1 in the genus Betacoronavirus,subgenus Embecovirus.Other members of the species Betacoronavirus 1 comprise porcine hemagglutinating encephalomyelitis virus(PHEV),human coronavirus OC43(HCoV-OC43),equine coronavirus(ECoV),and rabbit coronavirus HKU14(RbCoV HKU14)(Corman et al.,2018).BCoV is known to infect a wide range of mammals including domestic and wild ruminants,causing en-teritis and pneumonia(Saif,2010).BCoV is ubiquitous in cattle world-wide,even in the respiratory and intestinal samples of healthy individuals,causing major economic losses to the beef and dairy cattle industries(Vlasova and Saif,2021).Importantly,it has been suggested that HCoV-OC43 originated in rodents,and that the major host of BCoV-cattle-acts as intermediate host(Kin et al.,2016;Forni et al.,2017;Corman et al.,2018;Cui et al.,2019).