Prospective evaluation of laparoscopic Roux en Y gastric bypass in patients with clinically severe obesity
- Author:
- No author available
- Journal Title:
- WORLD JOURNAL OF GASTROENTEROLOGY
- Issue:
- 39
- DOI:
- 10.3748/wjg.14.6024
- Key Word:
- Laparoscopic gastric bypass;Evaluation;Obesity
Abstract： AIM: To evaluate and present our experience with laparoscopic Roux en Y gastric bypass (RYGB) in a selected patient population.METHODS: A cohort of 130 patients with a body mass index (BMI) between 35 and 50 kg/m2 were evaluated in relation to postoperative morbidity, weight loss and resolution of co-morbidities for a period of 4 years following laparoscopic RYGB.RESULTS: Early morbidity was 10.0%, including 1 patient with peritonitis who was admitted to Intensive Care Unit (ICU) and 1 conversion to open RYGB early in the series. There was no early or late mortality. Maximum weight loss was achieved at 12 mo postoperatively, with mean BMI 30 kg/m2, mean percentage of excess weight loss (EWL%) 66.4% and mean percentage of initial weight loss (IWL%) 34.3% throughout the follow-up period. The majority of preexisting comorbidities were resolved after weight loss and no major metabolic disturbances or nutritional deficiencies were observed.CONCLUSION: Laparoscopic RYGB appears to be a safe and effective procedure for patients with BMI 35-50 kg/m2 with results that are comparable to previously published data mostly from the USA but from Europe as well.
- [1]Vagenas K,Kalfarentzos F,Alexandrides TK,etc.Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a prospective, double blind study.[J].2008,247(3).
- [2]Rachel L, Batterham,Michael A, Cowley,Caroline J, Small,etc.Gut hormone PYY(3-36) physiologically inhibits food intake.[J].2002,418(6898).
- [3]Schoelles K,Fahrbach K,Braunwald E,etc.Bariatric surgery: a systematic review and meta-analysis.[J].2004,292(14).
- [4]Eric J, DeMaria.Bariatric surgery for morbid obesity.[J].2007,356(21).
- [5]C W, le Roux,R L, Batterham,S J B, Aylwin,etc.Attenuated peptide YY release in obese subjects is associated with reduced satiety.[J].2006,147(1).
- [6]Ikramuddin S,Schauer P,Hamad G,etc.The learning curve for laparoscopic Roux-en-Y gastric bypass is 100 cases.[J].2003,17(2).
- [7]A, Westling,S, Gustavsson.Laparoscopic vs open Roux-en-Y gastric bypass: a prospective, randomized trial.[J].2001,11(3).
- [8]Vagenakis AG,Kalfarentzos F,Alexandrides TK,etc.Restoration of euglycemia and normal acute insulin response to glucose in obese subjects with type 2 diabetes following bariatric surgery.[J].2003,52(5).
- [9]Juan A, Luján,M Dolores, Frutos,Quiteria, Hernández,etc.Laparoscopic versus open gastric bypass in the treatment of morbid obesity: a randomized prospective study.[J].2004,239(4).
- [10]Ghatei MA,Bloom SR,Chanoine JP,etc.Ghrelin, peptide YY, glucose-dependent insulinotropic polypeptide, and hunger responses to a mixed meal in anorexic, obese, and control female adolescents.[J].2005,90(4).
- [11]Withers DJ,Ghatei MA,Batterham RL,etc.Inhibition of food intake in obese subjects by peptide YY3-36.[J].2003,349(10).
- [12]Carel W, le Roux,Simon J B, Aylwin,Rachel L, Batterham,etc.Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters.[J].2006,243(1).
- [13]Jones DB,Smith CD,Morgenstern L,etc.Optimal management of the morbidly obese patient. SAGES appropriateness conference statement.[J].2004,18(7).
- [14]Nguyen NT,Varela E,Sabio A,etc.Resolution of hyperlipidemia after laparoscopic Roux-en-Y gastric bypass.[J].2006,203(1).
- [15]Alan C Wittgrove,G Wesley ClarkLaurier J Tremblay.Laparoscopic Gastric Bypass, Roux-en-Y: Preliminary Report of Five Cases[J].1994,4(4).
- [16]Katherine A, Elder,Bruce M, Wolfe.Bariatric surgery: a review of procedures and outcomes.[J].2007,132(6).