Abstract： AIM:To observe the clinical efficacy of 8-0 polypropylene scleral-sutured fixed intraocular lens(IOL)suspension implantation with the double knots technique in aphakic eyes.METHODS:Retrospective case series study.The data of 30 aphakic cases(31 eyes,22 males)that underwent IOL suspension in our hospital from January 2021 to November 2022 were collected.The suspension of IOL(AcrySof IQ or Tecnis ZCB00)was performed by 8-0 polypropylene scleral-sutured with the double knots technique.The visual acuity,intraocular pressure(IOP),IOL position and complications with at least 6 mo of follow-up were observed.RESULTS:The mean preoperative uncorrected visual acuity(UCVA,LogMAR)and best-corrected visual acuity(BCVA,LogMAR)were 2.53±0.78 and 0.35±0.26,respectively,which were 0.58±0.26 and 0.36±0.27 at 6 mo postoperatively,respectively.And the differences in UCVA were statistically significant(t=15.408,P＜0.01),whereas the difference in BCVA was not(t=-1.677,P=0.104).There were no intraoperative complications,with IOL position all centered,but 3 eyes had IOL tilt,2 eyes had intraocular hypertension,5 eyes had corneal edema,and 1 eye had suture exposure postoperatively.There were no complications such as hyphema,vitreous hemorrhage,macular edema,corneal endothelial decompensation,hypotony,choroidal detachment,retinal detachment,fulminant superior choroidal hemorrhage,endophthalmitis,or others.CONCLUSION:The 8-0 polypropylene scleral-sutured fixed intraocular lens suspension implantation with the double knots technique can improve the postoperative visual acuity of aphakic patients,and fewer complications,which is an option for the treatment of aphakia,dislocation of the lens and ligament abnormalities.